Projects

The bumpy road to treating multiple sclerosis with stem cells
Mixed messages surrounding their clinical benefits threatened the legitimacy of stem cell therapies for multiple sclerosis, but there is still plenty of promise.
Targeting nutrient signaling in the gut to tackle metabolic disease
A new oral bead technology is designed to stimulate nutrient-sensing cells in discrete parts of the gut to restore metabolic balance.
Modifying macrophages to attack solid tumors
A team of industry and academic researchers developed a new way to engineer the immune system, leading to the first clinical trial using genetically modified macrophages.
Electric fields disrupt cancer cell division
A novel, non-invasive treatment using electrical currents exploits physiological properties of dividing cancer cells to prolong survival and augment current therapies.
RNA interference: Discovery, development, and applications
Conserved across plants and animals, RNAi is a powerful mechanism with tremendous therapeutic potential.
On the Road to Treating Mitochondrial Diseases
Recent advancements in mitochondrial genome editing technologies take scientists one step closer to developing viable treatments for mitochondrial diseases, which affect 1 in 4300 adults.
Infographic: Understanding Bacteriophages
Ultra-microscopic viruses that selectively target and kill bacteria may mitigate antimicrobial resistance.
Antimicrobial Resistance: The Silent Pandemic
Scientists continue to ring alarm bells about the risks associated with the continued misuse of antimicrobials and advocate for innovative treatments, improved surveillance, and greater public health education.
Telomerase: The Protector of Chromosomes
Scientists found evidence of telomeres in the 1930s, but did not identify them until the 1970s. Since then, researchers’ understanding of telomeres and their role in DNA repair, aging, and disease has expanded exponentially.
Science Milestones: The First Transgenic Mice
Pivotal advancements in transgenic science in the 1970s and 80s helped launch the mouse as a model system for studying human development and disease.