Surveillance Gaps: How Cancer Arises

Link to download eBook: https://viewonline.the-scientist.com/surveillance-gaps-how-cancer-arises-10xgenomics-ebook-new-template

In this issue exploring mechanisms behind cancer cell immune evasion I contributed 2 science news article.

 

An Orchestrated Attack Helps Cancer Cells Evade Immune Defenses

Using CRISPR-Cas9 screening methods, scientists identified a core set of genes that boost cancer cell resistance to killer T cells

Reference: K.A. Lawson et al., “Functional genomic landscape of cancer-intrinsic evasion of killing by T cells,” Nature.

 

Tracing the Steps of Tumor Development

Single-cell sequencing methods help scientists characterize the cellular heterogeneity in solid tumors and reconstruct the trajectory of tumor progression.

Reference: S.D. Praktiknjo et al., “Tracing tumorigenesis in a solid tumor model at single-cell resolution,” Nature Communications.

Danielle Gerhard
Danielle Gerhard
Assistant Editor